The Phantom of Heilbronn and DNA testing.

Oops:

Police in Germany have admitted that a woman they have been hunting for more than 15 years may never have existed. Dubbed the “phantom of Heilbronn”, the woman was dubbed by police as the country’s most dangerous woman. Investigators had connected her to six murders and an unsolved death based on DNA traces found at the scene.

Police are now acknowledging that swabs used to collect DNA samples may have been contaminated by an innocent woman - possibly during manufacture.


Melanism in evolution

Sean Carroll in The Smithsonian Magazine talks about how the alternative color forms of some animals are providing new insights into how animals adapt and evolve:

One of the most widespread phenomena in the animal kingdom is the occurrence of darkly pigmented varieties within species. All sorts of moths, beetles, butterflies, snakes, lizards and birds have forms that are all or mostly black. Perhaps most familiar are the dark big cats, such as the black leopard and black jaguar. These beautiful animals are often displayed in zoos as curiosities, but they also occur in the wild in significant numbers.


The feeding biomechanics and dietary ecology of Australopithecus africanus

In today’s PNAS, The feeding biomechanics and dietary ecology of Australopithecus africanus:

The African Plio-Pleistocene hominins known as australopiths evolved a distinctive craniofacial morphology that traditionally has been viewed as a dietary adaptation for feeding on either small, hard objects or on large volumes of food. A historically influential interpretation of this morphology hypothesizes that loads applied to the premolars during feeding had a profound influence on the evolution of australopith craniofacial form.

Here, we test this hypothesis using finite element analysis in conjunction with comparative, imaging, and experimental methods. We find that the facial skeleton of the Australopithecus type species, A. africanus, is well suited to withstand premolar loads. However, we suggest that the mastication of either small objects or large volumes of food is unlikely to fully explain the evolution of facial form in this species.

Rather, key aspects of australopith craniofacial morphology are more likely to be related to the ingestion and initial preparation of large, mechanically protected food objects like large nuts and seeds. These foods may have broadened the diet of these hominins, possibly by being critical resources that australopiths relied on during periods when their preferred dietary items were in short supply.

Our analysis reconciles apparent discrepancies between dietary reconstructions based on biomechanics, tooth morphology, and dental microwear.


Phylogenetics in the NY Times

The NY Times has a nice article on phylogenetic tree visualisation. Yes, really:

For years now the researchers have sequenced DNA from thousands of species from jungles, tundras and museum drawers. They have used supercomputers to crunch the genetic data and have gleaned clues to how today’s diversity of baobobs, dandelions, mosses and other plants evolved over the past 450 million years. The pace of their progress gives Dr. Sanderson hope that they will draw the entire evolutionary tree of plants within the next few years. “It’s within striking distance,” Dr. Sanderson said.

There’s just one problem. “We have no way to visualize such a tree at the moment,” he said. If they tried, they would end up with a blurry, inscrutable thicket. “It would be ironic,” Dr. Sanderson said. “We’d be saying, ‘We’ve built it, but we can’t show it to you.’


Wednesday Wiki: The Bone Wars

The Bone Wars occurred during a period of intense fossil speculation and discovery during the Gilded Age of American history, marked by a heated rivalry between Edward Drinker Cope (of the Academy of Natural Sciences in Philadelphia) and Othniel Charles Marsh (of the Peabody Museum of Natural History at Yale). Each of the two paleontologists used underhanded methods to try to out-compete the other in the field, resorting to bribery, theft, and destruction of bones. Each scientist also attacked the other in scientific publications, seeking to ruin his credibility and have his funding cut off.


Is there more to heredity, natural selection, and evolution than genes and DNA

Eva Jablonka asks if there is more to heredity, natural selection, and evolution than genes and DNA?:

Growing evidence indicates there is more to heredity than DNA, that heritable non-DNA variations can take place during development, sometimes in response to an organism’s environment. The notion of soft inheritance is returning to reputable scientific inquiry. Moreover, there seem to be cellular mechanisms activated during periods of extreme stress that trigger bursts of genetic and non-genetic heritable variations, inducing rapid evolutionary change. These realizations promise to profoundly alter our view of evolutionary dynamics.


Bioinformatics: the news of my death has been greatly exaggerated

Lincoln Stein updates his 2003 prediction that bioinformatics would be dead in ten years:

In February 2003 I gave a keynote address for the second annual O’Reilly Bioinformatics Technology Conference called ‘Bioinformatics: Gone in 2012′ in which I predicted that bioinformatics as a discipline separate from mainstream biology would be gone in ten years. My talk was met with resentment, disappointment and stunned disbelief by an audience of computer geeks who had come to the conference for the express purpose of getting in on the hot new thing. Worse, this was the year in which biotech and pharma realized they had significantly overinvested in bioinformatics and started large-scale layoffs. In the light of a downsized bioinformatics market, the O’Reilly publishing house cancelled a series of planned bioinformatics textbooks, and never sponsored another Bioinformatics Technology Conference. It seemed as though my predictions had come true ten years early, and although I knew it was all coincidental, I couldn’t suppress the sinking feeling that I was the villain who triggered the collapse.