Fumerase deficiency in Utah & Arizona

Polygamist society faces rare genetic disorder:

  In a dusty neighborhood under sheer sandstone cliffs studded with juniper on the Arizona-Utah border, a rare genetic disorder is spreading through polygamous families on a wave of inbreeding.

The twin border communities of Hildale, Utah, and Colorado City, Arizona, have the world’s highest known prevalence of fumarase deficiency, an enzyme irregularity that causes severe mental retardation brought on by cousin marriage, doctors say.

Posted on timeJune 17th, 2007 by userSimon Greenhill



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